AR
Compact local exon/block record cluster
| MANE transcript | ENST00000374690.9 |
|---|---|
| ClinVar P/LP records | 365 |
| Low-record-burden flag | no |
| Unit rows | 37 |
Unit-level record coverage
| Unit type | Best record coverage | Estimated payload |
|---|---|---|
| Single exon | 31.0% | 2,742 bp |
| Adjacent exon block | 71.8% | 3,444 bp |
| Downstream-CDS | 69.6% | 1,144 bp |
Why this classification?
- Local exon/block coverage is 71.8% with an estimated payload of 3,444 bp.
- This label means record burden clusters in a local transcript interval.
How to read this page
Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.
Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.
Condition-associated pathogenic-record groups
Record-level ClinVar condition facets. These are not patient cohorts, disease prevalence, or patient coverage.
| Condition label | P/LP records | Condition architecture | Local coverage | Boundary-CDS coverage |
|---|---|---|---|---|
| Androgen resistance syndrome | 270 | Donor/payload-burden caveat | 0.725926 | 0.696296 |
| Kennedy disease | 161 | Donor/payload-burden caveat | 0.720497 | 0.670807 |
| Partial androgen insensitivity syndrome | 27 | Boundary-CDS payload architecture | 0.703704 | 0.851852 |