Start here

Use this page as a guided route through PrimeReplace Atlas. Each step links to the relevant browser page.

1. Search a gene

Start with a disease gene or locus that has already been identified.

Open gene search →

Example pages: DMD, F9, GLA, CFTR, BRCA1

2. Read the architecture label

The architecture label summarizes how ClinVar P/LP records are organized relative to transcript units.

Open architecture classes →

3. Check transcript-unit coverage

Compare single-exon, adjacent exon-block, and boundary-CDS coverage summaries.

Open opportunity units →

4. Review condition facets

Inspect ClinVar condition-associated record groups where condition-level architecture summaries are available.

Open condition facets →

5. Download source tables

Use release tables to trace gene-level summaries, condition-associated records, and validation outputs.

Open downloads →

6. Check methods, limitations, and citation

Review the resource stack, scope, and citation before reuse.

Methods → Limitations → Citation →

PrimeReplace Atlas Browser release 1.0.1.