ARSB
Compact local exon/block record cluster
| MANE transcript | ENST00000264914.10 |
|---|---|
| ClinVar P/LP records | 254 |
| Low-record-burden flag | no |
| Unit rows | 37 |
Unit-level record coverage
| Unit type | Best record coverage | Estimated payload |
|---|---|---|
| Single exon | 26.8% | 374 bp |
| Adjacent exon block | 76.4% | 1,204 bp |
| Downstream-CDS | 73.6% | 1,287 bp |
Why this classification?
- Local exon/block coverage is 76.4% with an estimated payload of 1,204 bp.
- This label means record burden clusters in a local transcript interval.
How to read this page
Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.
Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.
Condition-associated pathogenic-record groups
Record-level ClinVar condition facets. These are not patient cohorts, disease prevalence, or patient coverage.
| Condition label | P/LP records | Condition architecture | Local coverage | Boundary-CDS coverage |
|---|---|---|---|---|
| Mucopolysaccharidosis type 6 | 251 | Donor/payload-burden caveat | 0.760956 | 0.717131 |