CAST

Diffuse/moderate record architecture

MANE transcriptENST00000675179.1
ClinVar P/LP records51
Low-record-burden flagno
Unit rows180

Unit-level record coverage

Unit typeBest record coverageEstimated payload
Single exon3.9%99 bp
Adjacent exon block9.8%363 bp
Downstream-CDS25.5%2,103 bp

Why this classification?

How to read this page

Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.

Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.