CUBN
Large-payload / donor/payload-burden caveat
| MANE transcript | ENST00000377833.10 |
|---|---|
| ClinVar P/LP records | 206 |
| Low-record-burden flag | no |
| Unit rows | 391 |
Unit-level record coverage
| Unit type | Best record coverage | Estimated payload |
|---|---|---|
| Single exon | 5.8% | 210 bp |
| Adjacent exon block | 12.6% | 939 bp |
| Downstream-CDS | 100.0% | 10,747 bp |
Why this classification?
- Downstream-CDS record coverage is 100.0%, but the estimated downstream payload is 10,747 bp (5–20 kb).
- This label emphasizes payload or evidence burden rather than compact architecture.
How to read this page
Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.
Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.