DDX3X
Compact downstream-CDS record-coverage hypothesis
| MANE transcript | ENST00000644876.2 |
|---|---|
| ClinVar P/LP records | 366 |
| Low-record-burden flag | no |
| Unit rows | 91 |
Unit-level record coverage
| Unit type | Best record coverage | Estimated payload |
|---|---|---|
| Single exon | 14.8% | 182 bp |
| Adjacent exon block | 49.7% | 751 bp |
| Downstream-CDS | 97.8% | 1,941 bp |
Why this classification?
- Downstream-CDS record coverage is 97.8% with an estimated payload of 1,941 bp (≤5 kb).
- This label is boundary-based: high coverage can occur when many coding records lie downstream of an early transcript boundary.
How to read this page
Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.
Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.
Condition-associated pathogenic-record groups
Record-level ClinVar condition facets. These are not patient cohorts, disease prevalence, or patient coverage.
| Condition label | P/LP records | Condition architecture | Local coverage | Boundary-CDS coverage |
|---|---|---|---|---|
| Intellectual disability, X-linked 102 | 177 | Local compact architecture | 0.531073 | 0.971751 |
| Inborn genetic diseases | 47 | Local compact architecture | 0.574468 | 0.978723 |