MEGF8
Downstream-CDS high-coverage with context burden
| MANE transcript | ENST00000251268.11 |
|---|---|
| ClinVar P/LP records | 43 |
| Low-record-burden flag | no |
| Unit rows | 241 |
Unit-level record coverage
| Unit type | Best record coverage | Estimated payload |
|---|---|---|
| Single exon | 11.6% | 3,259 bp |
| Adjacent exon block | 20.9% | 3,887 bp |
| Downstream-CDS | 97.7% | 8,348 bp |
Why this classification?
- Downstream coverage is high, but boundary, splice, dosage, or context assumptions dominate interpretation.
How to read this page
Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.
Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.