MKS1
Compact downstream-CDS record-coverage hypothesis
| MANE transcript | ENST00000393119.7 |
|---|---|
| ClinVar P/LP records | 181 |
| Low-record-burden flag | no |
| Unit rows | 97 |
Unit-level record coverage
| Unit type | Best record coverage | Estimated payload |
|---|---|---|
| Single exon | 10.5% | 110 bp |
| Adjacent exon block | 35.4% | 540 bp |
| Downstream-CDS | 94.5% | 1,597 bp |
Why this classification?
- Downstream-CDS record coverage is 94.5% with an estimated payload of 1,597 bp (≤5 kb).
- This label is boundary-based: high coverage can occur when many coding records lie downstream of an early transcript boundary.
How to read this page
Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.
Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.