PCLO
Downstream-CDS high-coverage with context burden
| MANE transcript | ENST00000333891.14 |
|---|---|
| ClinVar P/LP records | 73 |
| Low-record-burden flag | no |
| Unit rows | 139 |
Unit-level record coverage
| Unit type | Best record coverage | Estimated payload |
|---|---|---|
| Single exon | 24.7% | 5,080 bp |
| Adjacent exon block | 71.2% | 10,864 bp |
| Downstream-CDS | 100.0% | 15,178 bp |
Why this classification?
- Downstream coverage is high, but boundary, splice, dosage, or context assumptions dominate interpretation.
How to read this page
Record coverage summarizes ClinVar P/LP records mapped to this gene. It does not estimate patient coverage, editing efficiency, therapeutic efficacy, or safety.
Downstream-CDS values are transcript-boundary hypotheses. High downstream coverage can be boundary-driven and should be read with payload and context burden.